Individual Research Projects


University of Genova – Department of Internal Medicine and Medical Specialities, Genova, ITALY
Individual project title: Strategies for reducing NAPRT activity and sensitize ovarian cancer to NAMPT inhibitors
Supervisor: Prof. Alessio Nencioni


University of Genova – Department of Experimental Medicine, Section of Biochemistry, Genova, ITALY
Individual project title: Optimization of SIRT6 inhibitors and PoC studies in a skin field cancerization model
Supervisor: Prof. Santina Bruzzone


University of Bonn, Centre for Integrated Oncology, Bonn, GERMANY
Individual project title: NAPRT inhibition for PDAC sensitization to NAMPT inhibitors and chemotherapeutics
Supervisor: Prof. Georg Feldmann


University of Sheffield, Department of Oncology, Sheffield, UK
Individual project title: Evaluation and testing of small molecule NUDT22 inhibitors for uses in cancer
Supervisor: Prof. Thomas Helleday


Centre Hospitalier Universitaire Vaudois (CHUV), Service and central laboratory of Haematology, Lausanne, SWITZERLAND
Individual project title: Proof-of-concept studies of activity of new NAMPT inhibitors in haematological cancer models
Supervisor: Prof. Michel Duchosal


University of Geneva, Department of Pathology and Immunology, Geneva, SWITZERLAND
Individual project title: In vivo metastasis and angiogenesis imaging as a reading frame for NAMPT inhibitor activity
Supervisor: Prof. Christoph Scheiermann


University of Torino, Department of Medical Sciences, Torino, ITALY
Individual project title: Targeting the CD73-dependent nucleotide-metabolizing pathway in the tumor microenvironment
Supervisor: Prof. Silvia Deaglio


University of Sevilla, Department of Organic Chemistry, Sevilla, SPAIN
Individual project title: FK866 analogues as potential anti-cancer drugs
Supervisor: Prof. Inmaculada Robina


University of Trento, Centre of Integrative Biology, Trento, ITALY
Individual project title: Annotating and overcoming resistance to NAMPT inhibitors in cancer cells
Supervisor: Prof. Alessandro Provenzani


University Medical Center Hamburg-Eppendorf, Department of Biochemistry and Molecular Cell Biology, Hamburg, GERMANY
Individual project title: TRPM2 inhibition as a novel anticancer approach
Supervisor: Prof. Andreas Guse


University of Montpellier, Institute of Biomolecules Max Mousseron, Montpellier, FRANCE
Individual project title: Imino-C-glycosides as NAMPT inhibitor and potential anti-cancer agents
Supervisor: Prof. Alberto Marra


Innovamol Srls, Bologna, ITALY
Individual project title: Development of new, potent NAPRT inhibitors by CADD
Supervisor: Dr. Alberto Del Rio


NovImmune SA, Geniva, SWITZERLAND
Individual project title: Development and testing of anti-eNAMPT neutralizing monoclonal antibodies
Supervisor: Dr. Nicholas Fisher


Heidelberg Pharma GmbH, Heidelberg, GERMANY
Individual project title: Development of antibody-drug conjugates of NAMPT inhibitors for treating haematological cancers
Supervisor: Dr. Andreas Pahl

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